| # | Eastern Conference | PTS | GP | W | T | L | GS | GC | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  FC Cincinnati | 69 | 34 | 20 | 9 | 5 | 57 | 39 | DWDWL |
| 2 |  Orlando City SC | 63 | 34 | 18 | 9 | 7 | 55 | 39 | WWWWL |
| 3 |  Columbus Crew | 57 | 34 | 16 | 9 | 9 | 67 | 46 | LWWWW |
| 4 | Philadelphia Union | 55 | 34 | 15 | 10 | 9 | 57 | 41 | DLWWL |
| 5 |  New England Revolution | 55 | 34 | 15 | 10 | 9 | 58 | 46 | LLWLL |
| 6 |  Atlanta United FC | 51 | 34 | 13 | 12 | 9 | 66 | 53 | DDLWL |
| 7 |  Nashville SC | 49 | 34 | 13 | 10 | 11 | 39 | 32 | DWLLL |
| 8 |  New York Red Bulls | 43 | 34 | 11 | 10 | 13 | 36 | 39 | WWWLD |
| 9 |  Charlotte | 43 | 34 | 10 | 13 | 11 | 45 | 52 | WWDWL |
| 10 |  Montreal Impact | 41 | 34 | 12 | 5 | 17 | 36 | 52 | LLDWL |
| 11 |  New York City FC | 41 | 34 | 9 | 14 | 11 | 35 | 39 | WWDLW |
| 12 |  DC United | 40 | 34 | 10 | 10 | 14 | 45 | 49 | DLDLW |
| 13 |  Chicago Fire | 40 | 34 | 10 | 10 | 14 | 39 | 51 | DWWLL |
| 14 |  Inter Miami | 34 | 34 | 9 | 7 | 18 | 41 | 54 | DLLDL |
| 15 |  Toronto FC | 22 | 34 | 4 | 10 | 20 | 26 | 59 | LLLLL |
| # | Western Conference | PTS | GP | W | T | L | GS | GC | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  St. Louis City | 56 | 34 | 17 | 5 | 12 | 62 | 45 | WLLLL |
| 2 |  Seattle Sounders | 53 | 34 | 14 | 11 | 9 | 41 | 32 | WWLWL |
| 3 | Los Angeles FC | 52 | 34 | 14 | 10 | 10 | 54 | 39 | WWWWL |
| 4 |  Houston Dynamo | 51 | 34 | 14 | 9 | 11 | 51 | 38 | WDDWL |
| 5 |  Real Salt Lake | 50 | 34 | 14 | 8 | 12 | 48 | 50 | DWLDD |
| 6 |  Vancouver Whitecaps | 48 | 34 | 12 | 12 | 10 | 55 | 48 | WDDLL |
| 7 |  FC Dallas | 46 | 34 | 11 | 13 | 10 | 41 | 37 | DWLWL |
| 8 |  Sporting Kansas City | 44 | 34 | 12 | 8 | 14 | 48 | 51 | WDWWL |
| 9 |  San Jose Earthquakes | 44 | 34 | 10 | 14 | 10 | 39 | 43 | DDDDD |
| 10 |  Portland Timbers | 43 | 34 | 11 | 10 | 13 | 46 | 58 | WWDLL |
| 11 |  Minnesota United FC | 41 | 34 | 10 | 11 | 13 | 46 | 51 | LDLWL |
| 12 |  Austin | 39 | 34 | 10 | 9 | 15 | 49 | 55 | DLWLD |
| 13 |  Los Angeles Galaxy | 36 | 34 | 8 | 12 | 14 | 51 | 67 | DLLDL |
| 14 |  Colorado Rapids | 27 | 34 | 5 | 12 | 17 | 26 | 54 | DWLDL |
