| # | Eastern Conference | PTS | GP | W | T | L | GS | GC | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Louisville City | 76 | 34 | 24 | 4 | 6 | 86 | 43 | WDWWL |
| 2 |  Charleston Battery | 64 | 34 | 18 | 10 | 6 | 68 | 35 | DWWWL |
| 3 |  Detroit City | 56 | 34 | 15 | 11 | 8 | 46 | 32 | DDWWD |
| 4 | Indy Eleven | 51 | 34 | 14 | 9 | 11 | 49 | 50 | WDWLL |
| 5 |  Rhode Island | 51 | 34 | 12 | 15 | 7 | 56 | 41 | WWWWL |
| 6 |  Tampa Bay Rowdies | 50 | 34 | 14 | 8 | 12 | 55 | 46 | LDWDL |
| 7 |  Pittsburgh Riverhounds | 48 | 34 | 12 | 12 | 10 | 41 | 28 | WWWWL |
| 8 |  North Carolina | 48 | 34 | 13 | 9 | 12 | 54 | 43 | WLWWL |
| 9 |  Birmingham Legion | 45 | 34 | 13 | 6 | 15 | 44 | 51 | DLLLW |
| 10 |  Hartford Athletic | 44 | 34 | 12 | 8 | 14 | 39 | 52 | LWWDL |
| 11 |  Loudoun United | 42 | 34 | 11 | 9 | 14 | 44 | 39 | WLDLL |
| 12 |  Miami FC | 11 | 34 | 3 | 2 | 29 | 26 | 89 | LLLLL |
| # | Western Conference | PTS | GP | W | T | L | GS | GC | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1 | New Mexico United | 59 | 34 | 18 | 5 | 11 | 46 | 44 | DDLWL |
| 2 |  Colorado Springs | 52 | 34 | 15 | 7 | 12 | 48 | 40 | WWWWW |
| 3 |  Memphis 901 | 51 | 34 | 14 | 9 | 11 | 52 | 41 | DDWWL |
| 4 |  Las Vegas Lights | 50 | 34 | 13 | 11 | 10 | 49 | 46 | LLDWL |
| 5 |  Sacramento Republic | 49 | 34 | 13 | 10 | 11 | 46 | 34 | DDLLD |
| 6 |  Orange County SC | 46 | 34 | 13 | 7 | 14 | 38 | 45 | WDWWL |
| 7 |  Oakland Roots | 44 | 34 | 13 | 5 | 16 | 37 | 57 | DLWLL |
| 8 |  Phoenix Rising | 42 | 34 | 11 | 9 | 14 | 33 | 39 | WWLLL |
| 9 |  San Antonio | 39 | 34 | 10 | 9 | 15 | 36 | 49 | WDWDL |
| 10 |  Tulsa Roughnecks | 38 | 34 | 9 | 11 | 14 | 33 | 48 | LLDLW |
| 11 |  Monterey Bay | 34 | 34 | 8 | 10 | 16 | 29 | 44 | LWDLL |
| 12 |  El Paso Locomotive | 32 | 34 | 8 | 8 | 18 | 27 | 46 | WDLWL |
