| # | Group Stage | MP | W | D | L | GS | GC | PTS | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Tampa Bay Rowdies | 19 | 12 | 5 | 2 | 36 | 19 | 41 | LDWWW |
| 1 |  Orange County SC | 19 | 9 | 7 | 3 | 29 | 22 | 34 | DDWWL |
| 2 |  San Antonio | 19 | 8 | 8 | 3 | 26 | 21 | 32 | DLWWD |
| 2 |  Charleston Battery | 19 | 10 | 3 | 6 | 38 | 24 | 33 | LDLWW |
| 3 | New Mexico United | 16 | 9 | 3 | 4 | 25 | 17 | 30 | WWWWW |
| 3 |  Detroit City | 18 | 9 | 4 | 5 | 26 | 17 | 31 | WWLDW |
| 4 |  Tulsa Roughnecks | 18 | 8 | 5 | 5 | 20 | 17 | 29 | WDWWL |
| 4 |  Louisville City | 19 | 8 | 4 | 7 | 33 | 32 | 28 | WLWLD |
| 5 |  Lexington | 18 | 8 | 4 | 6 | 28 | 22 | 28 | LWDWW |
| 5 |  Pittsburgh Riverhounds | 19 | 8 | 3 | 8 | 20 | 20 | 27 | WLLWD |
| 6 |  Rhode Island | 17 | 7 | 4 | 6 | 27 | 19 | 25 | LWWLW |
| 6 |  El Paso Locomotive | 19 | 8 | 4 | 7 | 29 | 27 | 28 | LWLWW |
| 7 |  Miami FC | 20 | 5 | 7 | 8 | 24 | 32 | 22 | WLLDL |
| 7 |  Sacramento Republic | 18 | 7 | 6 | 5 | 24 | 16 | 27 | DWWLD |
| 8 |  Indy Eleven | 17 | 6 | 4 | 7 | 20 | 21 | 22 | LLLLD |
| 8 |  Las Vegas Lights | 19 | 7 | 5 | 7 | 26 | 27 | 26 | WWDDW |
| 9 |  Colorado Springs | 18 | 7 | 4 | 7 | 28 | 26 | 25 | WWWLL |
| 9 |  Hartford Athletic | 18 | 4 | 9 | 5 | 13 | 17 | 21 | DLDLD |
| 10 |  Oakland Roots | 20 | 5 | 7 | 8 | 25 | 29 | 22 | LLLDL |
| 10 |  Loudoun United | 18 | 3 | 9 | 6 | 21 | 30 | 18 | DDWWL |
| 11 |  Birmingham Legion | 17 | 3 | 8 | 6 | 18 | 21 | 17 | DLDLW |
| 11 |  Phoenix Rising | 19 | 5 | 7 | 7 | 24 | 26 | 22 | LWDDL |
| 12 |  Monterey Bay | 20 | 4 | 3 | 13 | 21 | 36 | 15 | LLLLL |
| 12 | Brooklyn | 17 | 3 | 4 | 10 | 17 | 32 | 13 | LWDLL |
| 13 |  Sporting JAX | 19 | 1 | 5 | 13 | 23 | 51 | 8 | DWDLL |
