| # | Conferencia Este | PTS | PJ | G | E | P | GF | GC | Forma |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Philadelphia Union | 66 | 34 | 20 | 6 | 8 | 57 | 35 | PGGGP |
| 2 |  FC Cincinnati | 65 | 34 | 20 | 5 | 9 | 52 | 40 | GGEGG |
| 3 | Inter Miami | 65 | 34 | 19 | 8 | 7 | 81 | 55 | EPGGG |
| 4 |  Charlotte | 59 | 34 | 19 | 2 | 13 | 55 | 46 | GPPGG |
| 5 |  New York City FC | 56 | 34 | 17 | 5 | 12 | 50 | 44 | GPGPP |
| 6 | Nashville SC | 54 | 34 | 16 | 6 | 12 | 58 | 45 | PPGEP |
| 7 |  Columbus Crew | 54 | 34 | 14 | 12 | 8 | 55 | 51 | PEPEG |
| 8 |  Chicago Fire | 53 | 34 | 15 | 8 | 11 | 68 | 60 | GGGEE |
| 9 |  Orlando City SC | 53 | 34 | 14 | 11 | 9 | 63 | 51 | GEEPP |
| 10 |  New York Red Bulls | 43 | 34 | 12 | 7 | 15 | 48 | 47 | PGPPP |
| 11 |  New England Revolution | 36 | 34 | 9 | 9 | 16 | 44 | 51 | EPGPE |
| 12 |  Toronto FC | 32 | 34 | 6 | 14 | 14 | 37 | 44 | EEEPG |
| 13 |  Montreal Impact | 28 | 34 | 6 | 10 | 18 | 34 | 60 | PPGEP |
| 14 |  Atlanta United FC | 28 | 34 | 5 | 13 | 16 | 38 | 63 | EPPPE |
| 15 |  DC United | 26 | 34 | 5 | 11 | 18 | 30 | 66 | EPPPE |
| # | Conferencia Oeste | PTS | PJ | G | E | P | GF | GC | Forma |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  San Diego | 63 | 34 | 19 | 6 | 9 | 64 | 41 | PEPGG |
| 2 |  Vancouver Whitecaps | 63 | 34 | 18 | 9 | 7 | 66 | 38 | EEGGP |
| 3 |  Los Angeles FC | 60 | 34 | 17 | 9 | 8 | 65 | 40 | GGGPE |
| 4 |  Minnesota United FC | 58 | 34 | 16 | 10 | 8 | 56 | 39 | GPEGP |
| 5 |  Seattle Sounders | 55 | 34 | 15 | 10 | 9 | 58 | 48 | PEGGG |
| 6 |  Austin | 47 | 34 | 13 | 8 | 13 | 37 | 45 | GPPGP |
| 7 |  FC Dallas | 44 | 34 | 11 | 11 | 12 | 52 | 55 | GEGPG |
| 8 |  Portland Timbers | 44 | 34 | 11 | 11 | 12 | 41 | 48 | PEEPP |
| 9 |  Real Salt Lake | 41 | 34 | 12 | 5 | 17 | 38 | 49 | PGGPE |
| 10 |  San Jose Earthquakes | 41 | 34 | 11 | 8 | 15 | 60 | 63 | PPGPG |
| 11 |  Colorado Rapids | 41 | 34 | 11 | 8 | 15 | 44 | 56 | GPEPE |
| 12 |  Houston Dynamo | 37 | 34 | 9 | 10 | 15 | 43 | 56 | PGPPE |
| 13 |  St. Louis City | 32 | 34 | 8 | 8 | 18 | 44 | 58 | GGPGE |
| 14 |  Los Angeles Galaxy | 30 | 34 | 7 | 9 | 18 | 46 | 66 | PGPGG |
| 15 |  Sporting Kansas City | 28 | 34 | 7 | 7 | 20 | 46 | 70 | PPPPE |
