| # | Conferencia Este | PJ | G | E | P | GF | GC | PTS | Forma |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Nashville SC | 18 | 12 | 4 | 2 | 35 | 14 | 40 | GGGPE |
| 2 |  Inter Miami | 18 | 11 | 5 | 2 | 45 | 32 | 38 | GGGGE |
| 2 |  Miami | 15 | 9 | 4 | 2 | 39 | 28 | 31 | |
| 3 |  New England Revolution | 17 | 9 | 3 | 5 | 28 | 21 | 30 | GPEGE |
| 4 | Chicago Fire | 17 | 9 | 2 | 6 | 32 | 23 | 29 | GGPPG |
| 5 |  New York City FC | 18 | 7 | 5 | 6 | 31 | 24 | 26 | EPGGE |
| 6 |  FC Cincinnati | 18 | 7 | 5 | 6 | 45 | 44 | 26 | EGGPG |
| 7 |  Charlotte | 18 | 7 | 4 | 7 | 29 | 27 | 25 | GGEGP |
| 8 |  New York Red Bulls | 18 | 7 | 4 | 7 | 29 | 39 | 25 | EGPPG |
| 9 |  DC United | 18 | 5 | 8 | 5 | 26 | 29 | 23 | EEEGE |
| 10 |  Orlando City SC | 18 | 6 | 2 | 10 | 30 | 47 | 20 | EPGGP |
| 11 |  Columbus Crew | 18 | 5 | 5 | 8 | 26 | 28 | 20 | EGPGE |
| 12 | Toronto FC | 18 | 3 | 8 | 7 | 24 | 32 | 17 | PEEPE |
| 13 |  Philadelphia Union | 18 | 4 | 4 | 10 | 25 | 33 | 16 | EPGGG |
| 14 |  Montreal Impact | 18 | 4 | 4 | 10 | 24 | 35 | 16 | EEPPE |
| 15 |  Atlanta United FC | 18 | 3 | 3 | 12 | 19 | 33 | 12 | PPEPP |
| # | Conferencia Oeste | PJ | G | E | P | GF | GC | PTS | Forma |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Vancouver Whitecaps | 17 | 10 | 4 | 3 | 38 | 17 | 34 | PGPEE |
| 2 |  Los Angeles FC | 19 | 10 | 4 | 5 | 35 | 19 | 34 | GGGGE |
| 3 |  San Jose Earthquakes | 18 | 10 | 3 | 5 | 37 | 24 | 33 | PGPEP |
| 4 |  Houston Dynamo | 17 | 9 | 2 | 6 | 25 | 24 | 29 | GEEGG |
| 5 |  Real Salt Lake | 17 | 8 | 3 | 6 | 29 | 25 | 27 | GEPPE |
| 6 |  FC Dallas | 18 | 7 | 6 | 5 | 32 | 25 | 27 | GGEPE |
| 7 |  St. Louis City | 18 | 7 | 5 | 6 | 24 | 24 | 26 | GGGGE |
| 8 |  Portland Timbers | 18 | 7 | 3 | 8 | 33 | 33 | 24 | PGEGG |
| 9 |  Seattle Sounders | 17 | 7 | 3 | 7 | 20 | 22 | 24 | PPPPP |
| 10 |  Minnesota United FC | 18 | 6 | 6 | 6 | 20 | 25 | 24 | PEPEE |
| 11 |  Colorado Rapids | 18 | 7 | 1 | 10 | 27 | 25 | 22 | PPGPG |
| 12 |  Los Angeles Galaxy | 19 | 5 | 7 | 7 | 24 | 29 | 22 | EPPEE |
| 13 |  San Diego | 18 | 5 | 6 | 7 | 32 | 29 | 21 | EPPGE |
| 14 |  Austin | 18 | 4 | 5 | 9 | 22 | 36 | 17 | PPGPP |
| 15 |  Sporting Kansas City | 18 | 4 | 2 | 12 | 18 | 46 | 14 | PPGPP |
