| # | Conferencia Este | PJ | G | E | P | GF | GC | PTS | Forma |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Nashville SC | 22 | 16 | 4 | 2 | 47 | 17 | 52 | EGGGG |
| 2 |  Inter Miami | 22 | 12 | 6 | 4 | 56 | 41 | 42 | EPEPG |
| 2 |  Miami | 15 | 9 | 4 | 2 | 39 | 28 | 31 | |
| 3 |  Chicago Fire | 21 | 11 | 4 | 6 | 39 | 28 | 37 | GGGEE |
| 4 |  New England Revolution | 22 | 11 | 4 | 7 | 36 | 27 | 37 | PPGEG |
| 5 |  Charlotte | 22 | 10 | 5 | 7 | 40 | 32 | 35 | PGEGG |
| 6 |  FC Cincinnati | 22 | 8 | 7 | 7 | 49 | 51 | 31 | GEGEP |
| 7 |  New York City FC | 22 | 7 | 7 | 8 | 36 | 31 | 28 | EPPEE |
| 8 | New York Red Bulls | 22 | 7 | 5 | 10 | 32 | 46 | 26 | GPPEP |
| 9 |  Orlando City SC | 22 | 7 | 4 | 11 | 37 | 54 | 25 | PEPGE |
| 10 |  Toronto FC | 22 | 5 | 10 | 7 | 32 | 38 | 25 | EGEGE |
| 11 |  DC United | 22 | 5 | 10 | 7 | 28 | 36 | 25 | EEPPE |
| 12 |  Philadelphia Union | 22 | 6 | 6 | 10 | 34 | 39 | 24 | GGEEG |
| 13 |  Atlanta United FC | 22 | 6 | 3 | 13 | 25 | 38 | 21 | PGGGP |
| 14 |  Montreal Impact | 22 | 5 | 6 | 11 | 30 | 46 | 21 | EEGEP |
| 15 |  Columbus Crew | 22 | 5 | 5 | 12 | 31 | 39 | 20 | EPPPP |
| # | Conferencia Oeste | PJ | G | E | P | GF | GC | PTS | Forma |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Vancouver Whitecaps | 21 | 13 | 4 | 4 | 48 | 18 | 43 | EGPGG |
| 2 |  Houston Dynamo | 22 | 12 | 3 | 7 | 30 | 26 | 39 | GGGPE |
| 3 |  Los Angeles FC | 23 | 10 | 6 | 7 | 36 | 22 | 36 | EPPEE |
| 4 |  San Jose Earthquakes | 22 | 10 | 4 | 8 | 39 | 33 | 34 | PPPPE |
| 5 | FC Dallas | 22 | 9 | 7 | 6 | 41 | 37 | 34 | EGGPE |
| 6 |  St. Louis City | 22 | 9 | 7 | 6 | 33 | 30 | 34 | EGEGE |
| 7 |  Colorado Rapids | 22 | 10 | 1 | 11 | 31 | 28 | 31 | GGGPG |
| 8 |  San Diego | 22 | 8 | 6 | 8 | 40 | 33 | 30 | EGPGG |
| 9 |  Minnesota United FC | 22 | 7 | 8 | 7 | 30 | 32 | 29 | EEPGE |
| 10 |  Real Salt Lake | 21 | 8 | 4 | 9 | 34 | 33 | 28 | EEPPP |
| 11 |  Portland Timbers | 22 | 8 | 4 | 10 | 39 | 39 | 28 | GPGEP |
| 12 |  Seattle Sounders | 21 | 7 | 5 | 9 | 24 | 29 | 26 | PPPEE |
| 13 |  Los Angeles Galaxy | 23 | 6 | 8 | 9 | 28 | 35 | 26 | EPGEP |
| 14 |  Austin | 22 | 6 | 6 | 10 | 28 | 41 | 24 | PPGEG |
| 15 |  Sporting Kansas City | 22 | 4 | 3 | 15 | 20 | 54 | 15 | PPEPP |
