| # | Conferencia Este | PJ | G | E | P | GF | GC | PTS | Forma |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Nashville SC | 17 | 12 | 3 | 2 | 33 | 12 | 39 | VVVPE |
| 2 |  Inter Miami | 17 | 11 | 4 | 2 | 43 | 30 | 37 | VVVVE |
| 2 |  Miami | 15 | 9 | 4 | 2 | 39 | 28 | 31 | |
| 3 |  New England Revolution | 16 | 9 | 2 | 5 | 26 | 19 | 29 | VPEVE |
| 4 |  Chicago Fire | 16 | 8 | 2 | 6 | 30 | 22 | 26 | VVPPV |
| 5 |  New York City FC | 17 | 7 | 4 | 6 | 30 | 23 | 25 | EPVVE |
| 6 |  Charlotte | 17 | 7 | 4 | 6 | 28 | 25 | 25 | VVEVP |
| 7 |  FC Cincinnati | 17 | 6 | 5 | 6 | 41 | 42 | 23 | EVVPV |
| 8 |  New York Red Bulls | 17 | 6 | 4 | 7 | 26 | 37 | 22 | EVPPV |
| 9 |  DC United | 17 | 5 | 7 | 5 | 24 | 27 | 22 | EEEVE |
| 10 |  Orlando City SC | 17 | 6 | 2 | 9 | 28 | 44 | 20 | EPVVP |
| 11 |  Columbus Crew | 17 | 5 | 4 | 8 | 24 | 26 | 19 | EVPVE |
| 12 |  Toronto FC | 17 | 3 | 7 | 7 | 23 | 31 | 16 | PEEPE |
| 13 |  Montreal Impact | 17 | 4 | 3 | 10 | 22 | 33 | 15 | EEPPE |
| 14 |  Philadelphia Union | 17 | 3 | 4 | 10 | 22 | 31 | 13 | EPVVV |
| 15 |  Atlanta United FC | 17 | 3 | 3 | 11 | 17 | 30 | 12 | PPEPP |
| # | Conferencia Oeste | PJ | G | E | P | GF | GC | PTS | Forma |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Vancouver Whitecaps | 16 | 10 | 3 | 3 | 37 | 16 | 33 | PVPEE |
| 2 |  Los Angeles FC | 18 | 10 | 3 | 5 | 34 | 18 | 33 | VVVVE |
| 3 |  San Jose Earthquakes | 17 | 10 | 3 | 4 | 35 | 20 | 33 | PVPEP |
| 4 |  Real Salt Lake | 16 | 8 | 2 | 6 | 28 | 24 | 26 | VEPPE |
| 5 |  Houston Dynamo | 16 | 8 | 2 | 6 | 23 | 24 | 26 | VEEVV |
| 6 |  FC Dallas | 17 | 7 | 5 | 5 | 32 | 25 | 26 | VVEPE |
| 7 |  St. Louis City | 17 | 7 | 4 | 6 | 23 | 23 | 25 | VVVVE |
| 8 |  Seattle Sounders | 16 | 7 | 3 | 6 | 19 | 20 | 24 | PPPPP |
| 9 |  Minnesota United FC | 17 | 6 | 5 | 6 | 19 | 24 | 23 | PEPEE |
| 10 |  Portland Timbers | 17 | 6 | 3 | 8 | 31 | 32 | 21 | PVEVV |
| 11 |  Los Angeles Galaxy | 18 | 5 | 6 | 7 | 24 | 29 | 21 | EPPEE |
| 12 |  San Diego | 17 | 5 | 5 | 7 | 31 | 28 | 20 | EPPVE |
| 13 |  Colorado Rapids | 17 | 6 | 1 | 10 | 26 | 25 | 19 | PPVPV |
| 14 |  Austin | 17 | 4 | 5 | 8 | 22 | 35 | 17 | PPVPP |
| 15 |  Sporting Kansas City | 17 | 4 | 2 | 11 | 18 | 44 | 14 | PPVPP |
